Department of Chemical and Biological Engineering

Prof. Terence T W WONG's Publications

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Article

Wong, Ivy Hei Man; Chen, Zhenghui; Shi, Lulin; Lo, Claudia Tung Kei; Kang, Lei; Dai, Weixing; Wong, Terence Tsz Wai, "Deep learning-assisted low-cost autofluorescence microscopy for rapid slide-free imaging with virtual histological staining", Biomedical Optics Express, v.15, (4), April 2024, p. 2187-2201 (2024)

Zhang, Yan; Huang, Bingxin; Dai, Weixing; Kang, Lei; Tsang, Tsz Chun Victor; Wu, Jiajie; Lo, Tung Kei; Wong, Terence T. W., "Label-free and non-destructive histology of unprocessed biological tissues with ultraviolet single-plane illumination microscopy", APL Photonics, v. 9, (1), January 2024, article number 016116 (2024)

Chen, Zhenghui; Wong, Ivy Hei Man; Dai, Weixing; Lo, Claudia Tung Kei; Wong, Terence Tsz Wai, "Lung cancer diagnosis on virtual histologically stained tissue using weakly supervised learning", Modern Pathology, April 2024, article number 100487 (2024)

Huang, Bingxin; Wong, Terence T W, "Review of low-cost light sources and miniaturized designs in photoacoustic microscopy", Journal of biomedical optics, v. 29, Jan 2024 (2024)

Segawa, Shinsuke; Wu, Jiajie; Kwok, Tsz Kin; Wong, Tsz Wai; He, Xuewen; Tang, Benzhong, "Co-aggregation as A Simple Strategy for Preparing Fluorogenic Tetrazine Probes with On-Demand Fluorogen Selection", Angewandte Chemie - International Edition, December 2023, article number e202313930 (2023)

Kang, Lei; Yu, Wentao; Zhang, Yan; Chen, Zhenghui; Wong, Terence T. W., "Deep Learning Enables Rapid Whole-Organ Histological Imaging with Ultraviolet-Excited Sectioning Tomography", ACS Photonics, v. 10, (10), September 2023, p. 3541-3550 (2023)

Zhang, Yan; Huang, Bingxin; Wu, Jiajie; Wong, Tsz Wai, "Advances in optical microscopy revolutionize the practice of surgical pathology with rapid and non-destructive tissue assessment", European Physical Journal: Special Topics, February 2022 (2022)

Lei, Kang; Li, Xiufeng; Zhang, Yan; Wong, Tat Wah, "Deep Learning Enables Ultraviolet Photoacoustic Microscopy Based Histological Imaging with Near Real-Time Virtual Staining", Photoacoustics, v. 25, March 2022, article number 100308 (2022)

Li, Xiufeng; Kang, Lei; Lo, Tung Kei; Tsang, Tsz Chun Victor; Wong, Terence T .W., "High-Speed Ultraviolet Photoacoustic Microscopy for Histological Imaging with Virtual-Staining assisted by Deep Learning", Journal of Visualized Experiments, v. 2022, (182), April 2022, article number e3649 (2022)

Zhang, Yan; Kang, Lei; Wong, Hei Man; Dai, Weixing; Li, Xiufeng; Chan, Ronald C. K.; Hsin, Michael K. Y.; Wong, Tsz Wai, "High-Throughput, Label-Free and Slide-Free Histological Imaging by Computational Microscopy and Unsupervised Learning", Advanced Science, v. 9, (2), January 2022, article number 2102358 (2022)

Li, Xiufeng; Yeung, Kylie; Tsang, Tsz Chun Victor; Huang, Bingxin; Lo, Tung Kei; Wong, Tsz Wai, "Low-cost high-resolution photoacoustic microscopy of blood oxygenation with two laser diodes", Biomedical Optics Express, v. 13, (7), July 2022, p. 3893-3903 (2022)

Zhang, Yan; Kang, Lei; Lo, Tung Kei; Tsang, Tsz Chun Victor; Wong, Tsz Wai, "Rapid slide-free and non-destructive histological imaging of human cancer tissues using wide-field optical-sectioning microscopy", Biomedical Optics Express, v. 13, (5), April 2022, p. 2782-2796 (2022)

Wong, Hei Man; Zhang, Yan; Chen, Zhenghui; Kang, Lei; Wong, Tsz Wai, "Slide-free Histological Imaging by Microscopy with Ultraviolet Surface Excitation using Speckle Illumination", Photonics Research, v.10, (1), January 2022, p. 120-125 (2022)

Zhang, Yan; Kang, Lei; Yu, Wentao; Tsang, Tsz Chun Victor; Wong, Tsz Wai, "Three-dimensional label-free histological imaging of whole organs by microtomy-assisted autofluorescence tomography", iScience, v. 25, (1), January 2022, article number 103721 (2022)

Li, Xiufeng; Kot, Chun Kit; Tsang, Tsz Chun Victor; Lo, Claudia T.K.; Huang, Bingxin; Tian, Ye; Wong, Hei Man; Cheung, Helen H.Y.; Kang, Lei; Chang, Atta C.Y.; Wong, Tsz Wai, "Ultraviolet photoacoustic microscopy with tissue clearing for high-contrast histological imaging", Photoacoustics, v. 25, March 2022, article number 100313 (2022)

Chen, Zhenghui; Yu, Wentao; Wong, Ivy Hei Man; Wong, Tsz Wai, "Deep-learning-assisted microscopy with ultraviolet surface excitation for rapid slide-free histological imaging", Biomedical Optics Express, v. 12, (9), September 2021, p. 5920-5938 (2021)

Li, Xiufeng; Tsang, Tsz Chun Victor; Kang, Lei; Zhang, Yan; Wong, Tsz Wai, "High-speed high-resolution laser diode-based photoacoustic microscopy for in vivo microvasculature imaging", Visual Computing for Industry, Biomedicine, and Art, v. 4, January 2021, article number 1 (2021)

Tsang, Tsz Chun Victor; Li, Xiufeng; Wong, Tsz Wai, "A Review of Endogenous and Exogenous Contrast Agents Used in Photoacoustic Tomography with Different Sensing Configurations", Sensors, v. 20, (19), October 2020, article number 5595, p. 1-20 (2020)

Li, Xiufeng; Kang, Lei; Zhang, Yan; Wong, Tsz Wai, "High-speed label-free ultraviolet photoacoustic microscopy for histology-like imaging of unprocessed biological tissues", Optics Letters, v. 45, (19), 1 October 2020, p. 5401-5404 (2020)

Li, Yang; Wong, Tsz Wai; Shi, Junhui; Hsu, Hsun Chia; Wang, Lihong V., "Multifocal photoacoustic microscopy using a single-element ultrasonic transducer through an ergodic relay", Light: Science and Applications, v. 9 , (1), December 2020, article number 135 (2020)

Lu, Yu; Wong, Tsz Wai; Chen, Feng; Wang, Lidai, "Compressed Ultrafast Spectral-temporal Photography", Physical Review Letters, v. 122, (19), May 2019, article number 193904 (2019)

Shi, Junhui; Wong, Tsz Wai; He, Yun; Li, Lei; Zhang, Ruiying; Yung, Christopher S.; Hwang, Jeeseong; Maslov, Konstantin I.; Wang, Lihong Victory, "High-resolution, High-contrast Mid-infrared Imaging of Fresh Biological Samples With Ultraviolet-localized Photoacoustic Microscopy", Nature Photonics, May 2019 (2019)

Qu, Y.; Li, L.; Shen, Y.; Wei, X.; Wong, Tsz Wai; Hu, P.; Yao, J.; Maslov, K.; Wang, L.V., "Dichroism-sensitive Photoacoustic Computed Tomography", Optica, v. 5, (4), 2018, p. 495-501 (2018)

Cai, De; Wong, Tsz Wai; Zhu, Liren; Shi, Junhui; Chen, Sung-Liang; Wang, Lihong V., "Dual-view photoacoustic microscopy for quantitative cell nuclear imaging", Optics Letters, v. 43, (20), October 2018, p. 4875-4878 (2018)

Imai, T.; Shi, J.; Wong, Tsz Wai; Li, L.; Zhu, L.; Wang, L.V., "High-throughput Ultraviolet Photoacoustic Microscopy With Multifocal Excitation", Journal of Biomedical Optics, v. 23, (3), March 2018, article number 036007 (2018)

Liu, X.; Wong, Tsz Wai; Shi, J.; Ma, J.; Yang, Q.; Wang, L.V., "Label-free Cell Nuclear Imaging by Grüneisen Relaxation Photoacoustic Microscopy", Optics Letters, v. 43, (4), February 2018, p. 947-950 (2018)

Liu, Y.; Shen, Y.; Ruan, H.; Brodie, F.L.; Wong, Tsz Wai; Yang, C.; Wang, L.V., "Time-reversed Ultrasonically Encoded Optical Focusing Through Highly Scattering ex vivo Human Cataractous Lenses", Journal of Biomedical Optics, v. 23, (1), January 2018, article number 010501 (2018)

Wong, Tsz Wai; Zhang, R.; Hai, P.; Zhang, C.; Pleitez, M.A.; Aft, R.L.; Novack, D.V.; Wang, L.V., "Fast Label-free Multilayered Histology-like Imaging of Human Breast Cancer by Photoacoustic Microscopy", Science Advances, v. 3, (5), May 2017, article number e1602168 (2017)

Wong, Tsz Wai; Zhang, R.; Zhang, C.; Hsu, H.-C.; Maslov, K.I.; Wang, L.; Shi, J.; Chen, R.; Shung, K.K.; Zhou, Q.; Wang, L.V., "Label-free Automated Three-dimensional Imaging of Whole Organs by Microtomy-assisted Photoacoustic Microscopy", Nature Communications, v. 8, (1), December 2017, article number 1386 (2017)

Wong, Tsz Wai; Zhou, Y.; Garcia-Uribe, A.; Li, L.; Maslov, K.; Lin, L.; Wang, L.V., "Use of a Single Xenon Flash Lamp for Photoacoustic Computed Tomography of Multiple-centimeter-thick Biological Tissue Ex Vivo and a Whole Mouse Body in Vivo", Journal of Biomedical Optics, v. 22, (4), April 2017, article number 041003 (2017)

Lau, A.K.S.; Terence T. W. Wong; Shum, H.C.; Wong, K.K.Y.; Tsia, K.K., "Ultrafast microfluidic cellular imaging by optical time-stretch", Methods in Molecular Biology, v. 1389, 2016, p. 23-45 (2016)

Yao, J.; Wang, L.; Yang, J.-M.; Maslov, K.I.; Wong, Tsz Wai; Li, L.; Huang, C.-H.; Zou, J.; Wang, L.V., "High-speed Label-free Functional Photoacoustic Microscopy of Mouse Brain in Action", Nature Methods, v. 12, (5), April 2015, p. 407-410 (2015)

Lin, L.; Xia, J.; Wong, Tsz Wai; Li, L.; Wang, L.V., "In Vivo Deep Brain Imaging of Rats Using Oral-cavity Illuminated Photoacoustic Computed Tomography", Journal of Biomedical Optics, v. 20, (1), January 2015, article number 016019 (2015)

Wong, Tsz Wai; Lau, A.K.S.; Ho, K.K.Y.; Tang, M.Y.H.; Robles, J.D.F.; Wei, X.; Chan, A.C.S.; Tang, A.H.L.; Lam, E.Y.; Wong, K.K.Y.; Chan, G.C.F.; Shum, H.C.; Tsia, K.K., "Asymmetric-detection Time-stretch Optical Microscopy (ATOM) for Ultrafast High-contrast Cellular Imaging in Flow", Scientific Reports, v. 4, January 2014, article number 3656 (2014)

Wei, X.; Lau, A.K.S.; Wong, Tsz Wai; Zhang, C.; Tsia, K.K.M.; Wong, K.K.Y., "Coherent Laser Source for High Frame-Rate Optical Time-Stretch Microscopy at 1.0 μm", IEEE Journal on Selected Topics in Quantum Electronics, v. 20, (5), September 2014, article number 6722896 (2014)

Lau, A.K.S.; Wong, Tsz Wai; Ho, K.K.Y.; Tang, M.T.H.; Chan, A.C.S.; Wei, X.; Lam, E.Y.; Shum, H.C.; Wong, K.K.Y.; Tsia, K.K., "Interferometric Time-stretch Microscopy for Ultrafast Quantitative Cellular and Tissue Imaging at 1 μm", Journal of Biomedical Optics, v. 19, (7), July 2014, article number 076001 (2014)

Chan, A.C.S.; Wong, Tsz Wai; Wong, K.K.Y.; Lam, E.Y.; Tsia, K.K., "Speed-dependent Resolution Analysis of Ultrafast Laser-scanning Fluorescence Microscopy", Journal of the Optical Society of America B: Optical Physics, v. 31, (4), April 2014, p. 755-764 (2014)

Wong, Tsz Wai; Lau, A.K.S.; Kenneth K. Y. Wong; Tsia, K.K., "Optical Time-stretch Confocal Microscopy at 1 μm", Optics Letters, v. 37, (16), August 2012, p. 3330-3332 (2012)

Conference paper

Chen, Zhenghui; Wong, Hei Man; Kang, Lei; Dai, Weixing; Wong, Tsz Wai, "Development of computational high-throughput autofluorescence microscopy by pattern illumination using a low-cost light-emitting diode assisted by deep learning", Proceedings of the SPIE Label-free Biomedical Imaging and Sensing (LBIS) 2023, v. 12391, March 2023 (2023)

Li, Xiufeng; Huang, Bingxin; Yeung, Kylie; Tsang, Tsz Chun Victor; Lo, Tung Kei; Wong, Tsz Wai, "Dual-wavelength low-cost high-resolution photoacoustic microscopy system for blood oxygenation imaging", SPIE Proceedings, v. 12379, March 2023, article number 1237918 (2023)

Zhang, Yan; Huang, Bingxin; Kang, Lei; Tsang, Tsz Chun Victor; Lo, Tung Kei; Wong, Tsz Wai, "Intraoperative label-free tissue pathology with ultraviolet single-pane illumination microscopy", SPIE Proceedings, v. PC12368, March 2023, article number PC123680D (2023)

Wong, Hei Man; Dai, Weixing; Lo, Tung Kei; Chan, Chi Kwan; Wong, Tsz Wai, "Label-free multiple histochemical virtual staining enabled by multiwavelength autofluorescence microscopy and deep learning", Proceedings of SPIE, v. 12391, April 2023, article number 2647804 (2023)

Shi, Lulin; Zhang, Yan; Wong, Ivy Hei Man; Lo, Tung Kei; Wong, Terence Tsz Wai, "MulHiST: Multiple Histological Staining for Thick Biological Samples via Unsupervised Image-to-Image Translation", Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), v. 14225, October 2023, p. 735-744 (2023)

Huang, Bingxin; Kang, Lei; Tsang, Tsz Chun Victor; Lo, Tung Kei; Wong, Tsz Wai, "Quantitative and label-free hematological analysis by smartphone-based microscopy and deep Learning", SPIE Proceedings, v. 12387, March 2023, article number PC123870D (2023)

Wu, Wentao; Zhang, Yan; Kang, Lei; Lo, Tung Kei; Wong, Tsz Wai, "Rapid block-face serial sectioning tomography for automated three-dimensional histological imaging", (2023)

Shi, Lulin; Wong, Ivy H. M.; Lo, Claudia T. K.; Tsui, Lauren W. K.; Wong, Terence T. W., "Unsupervised Multiple Virtual Histological Staining from Label-Free Autofluorescence Images", Proceedings - International Symposium on Biomedical Imaging, v. 2023-April, April 2023, article number 10230731 (2023)

Wong, Hei Man; Dai, Weixing; Hsin, Michael K. Y.; Wong, Tsz Wai, "A novel, rapid, and slide-free microscopy for on-site intraoperative histologic examination for human lung cancer—an assistive technology to guide surgical strategy", (2022)

Zhang, Yan; Kang, Lei; Yu, Wentao; Tsang, Tsz Chun Victor; Wong, Tsz Wai, "Three-dimensional histological imaging without labels by microtomy-assisted autofluorescence tomography", (2022)

Wong, Tsz Wai; Cai, De; Zhu, Liren; Shi, Junhui; Chen, Sungliang; Wang, Lihong V., "Quantitative Cell Nuclear Imaging by Dual-view Optical-resolution Photoacoustic Microscopy", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 10878, 2019, article number 108780R (2019)

Wong, Tsz Wai; Zhang, R.; Hai, P.; Aft, R.L.; Novack, D.V.; Wang, L.V., "Photoacoustic Microscopy Enables Multilayered Histological Imaging of Human Breast Cancer Without Staining", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 10494, 2018, article number 1049443 (2018)

Wong, Tsz Wai; Zhang, R.; Hsu, H.-C.; Maslov, K.I.; Shi, J.; Chen, R.; Shung, K.K.; Zhou, Q.; Wang, L.V., "Whole-organ Atlas Imaged by Label-free High-resolution Photoacoustic Microscopy Assisted by a Microtome", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 10494, 2018, article number 104942N (2018)

Lin, L.; Xia, J.; Wong, Tsz Wai; Zhang, R.; Wang, L.V., "In vivo deep brain imaging of rats using oral-cavity illuminated photoacoustic computed tomography", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 9323, 2015, article number 93230G (2015)

Wong, Tsz Wai; Lau, A.K.S.; Tang, M.Y.H.; Ho, K.K.Y.; Wong, K.K.Y.; Shum, A.H.C.; Tsia, K.K., "Asymmetric-detection Time-stretch Optical Microscopy (ATOM) for High-contrast and High-speed Microfluidic Cellular Imaging", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 8947, 2014, article number 89471D (2014)

Wei, X.; Lau, A.K.S.; Wong, Tsz Wai; Zhang, C.; Tsia, K.K.; Wong, K.K.Y., "Coherent Laser Source for Optical Time-stretched Microscopy", Optics InfoBase Conference Papers, 2014 (2014)

Lau, A.K.S.; Terence T. W. Wong; Zhang, C.; Tsia, K.K.; Wong, K.K.Y., "Coherent laser source for optical time-stretched microscopy xiaoming wei1", Conference on Lasers and Electro-Optics Europe - Technical Digest, v. 2014-January, 2014, article number 6989695 (2014)

Chan, A.C.; Wong, Tsz Wai; Wong, K.K.Y.; Lam, E.Y.; Tsia, K.K., "Revisit Laser Scanning Fluorescence Microscopy Performance Under Fluorescence-lifetime-limited Regime", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 8947, 2014, article number 894726 (2014)

Wong, Tsz Wai; Lau, Kam Seng; Chan, Antony C. S.; Lam, Edmund Y.; Wong, Kenneth K. Y.; Tsia, Kevin K., "Interferometric Time-stretch Microscopy for Ultrafast Quantitative Cellular Imaging 1 μm", Optics in the Life Sciences, OSA Technical Digest, 2013, p. NW1B.4 (2013)

Lau, A.K.S.; Wong, Tsz Wai; Wong, K.K.Y.; Tsia, K.K., "Megahertz-scan-rate Quantitative Tissue Imaging by Interferometric Time-stretch Microscopy", Asia Communications and Photonics Conference, ACP, 2013 (2013)

Tsia, Kevin K.; Wong, Kenneth K. Y.; Lau, Andy K. S.; Wong, Tsz Wai, "Optical Time-Stretch Microscopy for ultrafast Optofluidic Imaging", 7th International Conference on Nanophotonics/3rd Conference on Advances in Optoelectronics and Micro/Nano Optics (ICNP/AOM 2013), Hong KOng, 19-23 May 2013 (2013)

Wong, Tsz Wai; Tang, Matthew Y. H.; Lau, Kam Seng; Chan, Antony C. S.; Lam, Edmund Y.; Wong, Kenneth K. Y.; Shum, Anderson H. C.; Tsia, Kevin K., "Ultrafast Flow Imaging by 1 μm Time-stretch Microscopy", Optics in the Life Sciences, OSA Technical Digest, 2013, p. NW1B.5 (2013)

Lau, A.K.S.; Wong, Tsz Wai; Ho, K.K.Y.; Tang, M.Y.H.; Robles, J.D.F.; Wei, X.; Chan, A.C.S.; Tang, A.H.L.; Lam, E.Y.; Wong, K.K.Y.; Chan, G.C.F.; Shum, H.C.; Tsia, K.K., "Ultrafast High-contrast Microfluidic Cellular Imaging by Asymmetric-detection Time-stretch Optical Microscopy (ATOM)", Optics InfoBase Conference Papers, 2013 (2013)

Wong, Tsz Wai; Lau, A.K.S.; Wong, K.K.Y.; Tsia, K.K., "Cellular Imaging by Time-stretch Confocal Microscopy in the 1μm Window", Frontiers in Optics, FIO 2012, 2012 (2012)

Wong, Tsz Wai; Qiu, Y.; Lau, A.K.S.; Xu, J.; Chan, A.C.S.; Wong, K.K.Y.; Tsia, K.K., "Cost-effective Approaches for High-resolution Bioimaging by Time-stretched Confocal Microscopy at 1μm", Progress in Biomedical Optics and Imaging - Proceedings of SPIE, v. 8553, 2012, article number 85531P (2012)

Wong, Tsz Wai; Chan, A.C.S.; Wong, K.K.Y.; Tsia, K.K., "Pixel Super-resolution in Serial Time-encoded Amplified Microscopy (STEAM)", 2012 Conference on Lasers and Electro-Optics, CLEO 2012, 2012, article number 6326133 (2012)

Wong, Tsz Wai; Chan, A.C.S.; Wong, K.K.Y.; Tsia, K.K., "Pixel super-resolution in serial time-encoded amplified microscopy (STEAM)", CLEO: Science and Innovations, CLEO_SI 2012, 2012, p. CTu3J.4-CTu3J.4 (2012)

Preprint

Yu, Wentao; Kang, Lei; Tsang, Tsz Chun Victor; Zhang, Yan; Wong, Hei Man; Wong, Tsz Wai, "Translational Rapid Ultraviolet-excited Sectioning Tomography for Whole-organ Multicolor Imaging with Real-time Molecular Staining", (2021)