Prof. Ying CHAU's Publications

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Article

Zhorabek, Fariza; Abesekara, Manisha Sandupama; Liu, Jianhui; Dai, Xin; Huang, Jinqing; Chau, Ying, "Construction of Multiphasic Membraneless Organelles towards Spontaneous Spatial Segregation and Directional Flow of Biochemical Reactions", Chemical Science, v. 14, (4), January 2023, p. 801-811 (2023)

Liu, Jianhui; Zhorabek, Fariza; Dai, Xin; Huang, Jinqing; Chau, Ying, "Minimalist Design of an Intrinsically Disordered Protein-Mimicking Scaffold for an Artificial Membraneless Organelle", ACS Central Science, v. 8, (4), April 2022, p. 493-500 (2022)

Liu, Jianhui; Zhorabek, Fariza; Chau, Ying, "Nucleic Acids Modulate Liquidity and Dynamics of Artificial Membraneless Organelles", ACS Macro Letters, v. 11, (4), April 2020, p. 562-567 (2022)

Huang, Xiaonan; Chau, Ying, "Enhanced Delivery of siRNA to Retinal Ganglion Cells by Intravitreal Lipid Nanoparticles of Positive Charge", Molecular Pharmaceutics, v. 18, (1), 4 January 2021, p. 377-385 (2021)

Chung, Jin Teng; Lau, Chi Ming Laurence; Chau, Ying, "The Effect Of Polysaccharide-Based Hydrogels On The Response Of Antigen-Presenting Cell Lines To Immunomodulators", Biomaterials Science, v. 9, (19), 7 October 2021, p. 6542-6554 (2021)

Xu, Jingting; Chau, Ying; Lee, Yi-kuen, "Phage-based electrochemical sensors: A review", Micromachines, v. 10, (12), December 2019, article number 855 (2019)

Lau, Chi Ming Laurence; Yu, Yu; Jahanmir, Ghodsiehsadat; Chau, Ying, "Controlled release technology for anti-angiogenesis treatment of posterior eye diseases: Current status and challenges", Advanced Drug Delivery Reviews, 4 April 2018 (2018)

Suen, Wai-Leung Langston; Chau, Ying, "Size- dependent internalisation of folate- decorated nanoparticles via the pathways of clathrin and caveolae- mediated endocytosis in ARPE-19 cells", Journal of Pharmacy and Pharmacology v. 66, April 2014, p. 564-573 (2014)

Li, Q. ; Chow, K.L. ; Chau, Y., "Three-dimensional self-assembling peptide matrix enhances the formation of embryoid bodies and their neuronal differentiation", Journal of biomedical materials research. Part A v. 102, (6), 2014, p. 1991-2000 (2014)

Jiang, Liguo; Wang, Weiping; Chau, Ying; Yao, Shuhuai, "Controllable formation of aromatic nanoparticles in a three-dimensional hydrodynamic flow focusing microfluidic device", RSC Advances. v. 3, (39), 2013, p. 17762-17769 (2013)

Li, Qianqian., Cheung, Wai Hung., Chow, King L., Ellis-Behnke, Rutledge G., Chau, Ying., "Factorial analysis of adaptable properties of self-assembling peptide matrix on cellular proliferation and neuronal differentiation of pluripotent embryonic carcinoma", Nanomedicine. v. 8, (5), July 2012, p. 748-756 (2012)

Yu, Yu., Chau, Ying., "One-Step "Click" Method for Generating Vinyl Sulfone Groups on Hydroxyl-Containing Water-Soluble Polymers", Biomacromolecules. v. 13, (3), March 2012, p. 937-942 (2012)

Wang, W., Chau, Y., "Self-assembly mediated platform for rapid and facile preparation of peptide-functionalized nanoparticles with high stability", Chemistry of materials. v. 24, (5), 2012, p. 946-953 (2012)

Li, Zhongyu., Chau, Ying., "A Facile Synthesis of Branched Poly(ethylene glycol) and its Heterobifunctional Derivatives", Polymer Chemistry. v. 2, (4), 2011, p. 873-878 (2011)

Wang, Weiping., Chau, Ying., "Efficient and facile formation of two-component nanoparticles via aromatic moiety directed self-assembly", Chemical communications (London. 1996). v. 47, (37), 2011, p. 10224-10226 (2011)

Li, Z., Chau, Y., "Synthesis of X(Y)-(EO)n-OCH3 type heterobifunctional and X(Y)-(EO)n-Z type heterotrifunctional poly(ethylene glycol)s", Bioconjugate chemistry. v. 22, (3), 2011, p. 518-522 (2011)

Ko, E.I., Chau, Y., "Integrating academic and mentoring support for the development of first-year ChE students in Hong Kong", Chemical Engineering Education. v. 44, (1), 2010, p. 44-50 (2010)

Li, Qianqian., Chau, Ying., "Neural differentiation directed by self-assembling peptide scaffolds presenting laminin-derived epitopes", Journal OF Biomedical Materials research PART A. v. 94A, (3), 2010, SEP 1, p. 688-699 (2010)

Li, Zhongyu., Chau, Ying., "Synthesis of heterobifunctional poly(ethylene glycol)s by an acetal protection method", Polymer Chemistry. v. 1, (10), 2010, p. 1599-1601 (2010)

Zhou, P., Li, Z., Chau, Y., "Synthesis, characterization, and in vivo evaluation of poly(ethylene oxide-co-glycidol)-platinate conjugate", European Journal of Pharmaceutical Sciences. v. 41, (3-4), 2010, p. 464-472 (2010)

Zhong, J., Chau, Y., "Synthesis, characterization, and thermodynamic study of a polyvalent lytic peptide-polymer conjugate as novel anticancer agent", Bioconjugate Chemistry. v. 21, (11), 2010, p. 2055-2064 (2010)

Cheung, A.C.Y., Yu, Y., Tay, D., Wong, H.S., Ellis-Behnke, R., Chau, Y., "Ultrasound-enhanced intrascleral delivery of protein", International Journal of Pharmaceutics. v. 401, (1-2), 2010, p. 16-24 (2010)

Wang, Weiping., Chau, Ying., "Biomimetic Self-assembly of Triskelion Peptide Analogues into Supramolecular Polyhedra", AIChE Annual Meeting. Nov 2009, Nashville, USA (2009)

Wang, Weiping., Chau, Ying., "Self-assembled peptide nanorods as building blocks of fractal patterns", Soft matter. v. 5, (24), 2009, p. 4893-4898 (2009)

Li, Zhongyu., Chau, Ying., "Synthesis of Linear Polyether Polyol Derivatives As New Materials for Bioconjugation", Bioconjugate chemistry. v. 20, (4), 2009, APR, p. 780-789 (2009)

Zhong, Jieying., Chau, Ying., "Antitumor activity of a membrane lytic peptide cyclized with a linker sensitive to membrane type 1-matrix metalloproteinase", Molecular cancer therapeutics. v. 7, (9), 2008, SEP, p. 2933-2940 (2008)

Wang, Weiping., Yang, Zhimou., Patanavanich, Siamrut., Xu, Bing., Chau, Ying., "Controlling self-assembly within nanospace for peptide nanoparticle fabrication", Soft matter. v. 4, (8), 2008, p. 1617-1620 (2008)

Chau, Ying., Luo, Ying., Cheung, Alex C. Y., Nagai, Yusuke., Zhang, Shuguang., Kobler, James B., Zeitels, Steven M., Langer, Robert., "Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides - A model for biofunctional scaffolds", Biomaterials. v. 29, (11), 2008, APR, p. 1713-1719 (2008)

Chau, Ying., Dang, N.M., Tan, F.E., Langer, R., "Investigation of targeting mechanism of new dextran-peptide-methotrexate conjugates using biodistribution study in matrix-metalloproteinase overexpressing tumor xenograft model", Journal of Pharmaceutical Sciences. v. 95, 2006, p. 541-551 (2006)

Chau, Ying., Padera, R.F., Dang, N.M., Langer, R., "Antitumor efficacy of a novel polymer peptide drug conjugate in human tumor xenograft models", International Journal of Cancer. v. 118, 2005, p. 1519-1526 (2005)

Chau, Ying., Tan, F.E., Langer, R., "Synthesis and characterization of dextran-peptide-methotrexate conjugates for tumor targeting via mediation by matrix-metalloproteinase II and matrixmetalloproteinase IX", Bioconjugate Chemistry. v. 15, (4), 2004, p. 931-941 (2004)

Sagar, S.L., Chau, Ying., Watson, M.P., Lee, A.L., "Case study: capacity challenges in chromatography-based purification of plasmid DNA", Scale-up and optimization in preparative chromatography. v. 88, 2003, p. 251 (2003)

Kohane, D.S., Holmes, G.L., Chau, Ying., Zurakowski, D., Langer, R., Cha, B.H., "Effectiveness of muscimol-containing microparticles against pilocarpine-induced focal seizures", Epilepsia. v. 43, 2002, p. 1462-1468 (2002)

Bothwell, M.K., Daughetee, S.D., Chau, Ying., Wilson, D.B., Walker L.P., "Binding capacities of Thermomonospora fusca E3,E4 and E5, the E3 binding domain, and Trichoderma ressei CBHI on Avicel and bacterial microcrystalline cellulose", Bioresources Technology. v. 60, 1997, p. 169-178 (1997)

Book chapter

Zhong, Jieying., Chau, Ying., "Enzyme-Sensitive Biomaterials for Drug Delivery", Comprehensive Biotechnology. Vol. 5 / Edited by Murray Moo-Young. Amsterdam : Elsevier, 2011, p. 605-624 (2011)

Conference paper

Xu, Jingting; Gao, Bo; Zhao, Cong; Zeng, Qinglu; Chau, Ying; Lee, Yi-kuen, "Synergy of Chemical Immobilization and AC Electrical Orientation of T4 Phage on a Micro Electrochemical Sensor for Bacteria Detection via Differential Pulse Voltammetry", 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018, v. 2, 2018, p. 773-775 (2018)

Ni, Rong; Chau, Ying, "Regulation of the Gene Transfection of Peptide/DNA Hybrid Artificial “virus” by Peptide Sequence Variation", Journal of Controlled Release, v. 259, August 2017, p. e117-e118 (2016)

Zhong, Jieying., Chau, Ying., "A polyelectrolyte complex between lytic peptide-polymer conjugate and PGA as an efficient metabolic stress-inducing polymeric agent", The 19th Hong Kong International Cancer Congress. Hong Kong, China, November 2012 (2012)

Chau, Ying., Wang, Weiping., "Aromatic-directed self-assembly of biofunctional nanoparticles", The International Conference of Young Researchers on Advanced Materials (ICYRAM). Singapore, July, 2012 (2012)

Yu, Yu., Chau, Ying., "Biodegradable Hyaluronic Acid in situ Hydrogel for Tissue Augmentation", Biomedical Engineering International Conference 2012. Hong Kong, China, Dec 2012 (2012)

Chau, Ying., "Engineering biomaterials for drug delivery to the posterior segment", The 27th Asia-Pacific Academy of Ophthalmology (APAO) meeting. Busan, Korea, April 2012 (2012)

Yu, Yu., Chau, Ying., "Hyaluronic acid based in situ hydrogel for controlled release of Avastin", The 8th International Symposium of Ophthalmology. Hong Kong, China, Dec 2012 (2012)

Chau, Ying., Yu, Yu., "Injectable hyaluronic acid-based hydrogel and its biomedical applications", The International Conference of Young Researchers on Advanced Materials (ICYRAM). Singapore, July 2012 (2012)

Chau, Ying., "Keynote speech: Engineering Biomaterials for Drug Delivery", BME2012 Biomedical Engineering International Conference. Hong Kong, December 2012 (2012)

Yu, Yu., Chau, Ying., "Preparation of hyaluronic acid based in situ hydrogel for protein delivery to the eye", The 9th World Biomaterials Congress. Chengdu, China, June 2012 (2012)

Li, Qian Qian., Chow, KL., Chau, Ying., "Three-dimensional self-assembling peptide matrix for forming and neuronal priming of totipotent embryonic body", The 9th World Biomaterials Congress. Chengdu, China, June 2012 (2012)

Jiang, Liguo., Wang, Weiping., Zeng, Yan., Qu, Jianan., Chau, Ying., Yao, Shuhuai., "Droplet-based microfluidics for synthesis of organic nanoparticles", the International Symposium on Microchemistry and Microsystems (ISMM 2011). Seoul, Korea, June 2-4, 2011 (2011)

Wang, Weiping., Chau, Ying., "Construction of soft nanocages from biomimetic self-assembly of bicomponent molecules", East Asian Postgraduate Workshop on Soft Matter. April 2010, Hong Kong (2010)

LI, CQ., Chow, KL., Chau, Y., "Dosage dependency of induced neuronal differentiation manipulated by the self assembly peptide niche", Tissue Engineering and Regenerative Medicine International Society (TERMIS), North America, 2010 Annual Conference. Orlando, Florida, USA. December 5-8, 2010 (2010)

Chau, Ying., "Enzyme-activated drug delivery systems", 6th LTS Academy Symposium on Unmet Needs in Personalized Medicines. May 2010, West Orange, NJ, USA (2010)

Yu, Yu., Chau, Ying., "Hyaluronic acid based in situ hydrogel for controlled delivery of protein to the posterior segment of the eye", The International Symposium on Ocular Pharmacology and Therapeutics. Macau, December, 2010 (2010)

Chau, Ying., "Investigation of the effects of ultrasound on protein transport through the sclera", The International Symposium on Ocular Pharmacology and Therapeutics. Macau, December, 2010 (2010)

Wong, Hoi Sang., Chau, Ying., "Ultrasound-mediated intrascleral drug delivery: Investigation on the effect of microbubbles", The International Symposium on Ocular Pharmacology and Therapeutics. Macau, December, 2010 (2010)

Tse, H.Y., Chau, Ying., "Ultrasound-mediated transscleral delivery of macromolecules: a study of changing ultrasound frequency and correlation with scleral pore size", The International Symposium on Ocular Pharmacology and Therapeutics. Macau, December, 2010 (2010)

Chau, Ying., "Anticancer polymer-linker-drug conjugates", 2nd World Cancer Congress. Beijing, China, June 2009 (2009)

Zhong, Jieying., Chau, Ying., "Antitumor activity of membrane-lytic peptides templated on a polymeric scaffold", 36th Annual Meeting and Exposition of the Controlled Release Society. July 2009, Copenhagen, Denmark (2009)

Wang, Weiping., Chau, Ying., "Construction of nanofibrous films from dipeptide-based hierarchical assembly", 1st Nano Today Conference. August 2009, Singapore (2009)

Chau, Ying., Li, Qianqian., "Designing Biofunctionalized Self-assembling Peptide Matrices to Engineer Extracellular Microenvironment", The 5th Sino-US Conference of Chemical Engineering, Fragrant Hill Hotel, Beijing, 13-16 Oct 2009 . (2009)

Chau, Ying., Li, Qianqian., "Engineering properties of self-assembling peptide matrices by incorporating peptide epitopes in building blocks", Biomaterials Asia. Hong Kong, April 2009 (2009)

Wang, Weiping., Chau, Ying., "Hollow vesicles self-assembled by short peptide derivatives", Faraday Discussion 143: Soft Nanotechnology, Royal Society of Chemistry. London UK, June 2009 (2009)

Wang, Weiping., Chau, Ying., "Mechanism for the self-assembly of fractal structures from dipeptide derivatives", Faraday Discussion 143: Soft Nanotechnology, Royal Society of Chemistry. London UK, June 2009 (2009)

Wang, Weiping., Chau, Ying., "Morphological control of self-assembling nanostructures by reverse microemulsion", Faraday Discussion 143: Soft Nanotechnology, Royal Society of Chemistry. London UK, June 2009 (2009)

Li, Qianqian., Chau, Ying., "Neural differentiation directed by self-assembling peptide matrix", WACBE World Congress on Bioengineering 2009. July 2009, Hong Kong (2009)

Yeung, Chris Wai Kit., Chau, Ying., "Optimization of protease-sensitivity of polymer vesicles", AIChE Annual Meeting. Nov 2009, Nashville, USA (2009)

Yeung, Wai Kit., Chau, Ying., "Peptide-modified block copolymer for the assembly of stimuli-responsive vesicles", Faraday Discussion 143: Soft Nanotechnology, Royal Society of Chemistry. London UK, June 2009 (2009)

Li, Zhongyu., Chau, Ying., "Polyether polyol -platinate conjugate and its micelle as new antitumor nanomedicines", WACBE World Congress on Bioengineering 2009. July 2009, Hong Kong (2009)

Li, Zhongyu., Chau, Ying., "Polyether polyol as a new macromolecular carrier in an anticancer polymer-drug conjugate", Biomaterials Asia. Hong Kong, April 2009 (2009)

Li, Zhongyu., Chau, Ying., "Polyether polyol derivatives as new bioconjugate carriers", AIChE Annual Meeting. Nov 2009, Nashville, USA (2009)

Zhong, Jieying., Chau, Ying., "Polymer-lytic peptide conjugate activated by tumor-associated protease", 36th Annual Meeting and Exposition of the Controlled Release Society. July 2009, Copenhagen, Denmark (2009)

Zhong, Jieying., Chau, Ying., "Polyvalent presentation of membrane-lytic peptides enhances antitumor potency", AIChE Annual Meeting. Nov 2009, Nashville, USA (2009)

Yeung, Chris Wai Kit., Chau, Ying., "Protease-sensitive polymer vesicles for drug delivery", AIChE Annual Meeting. Nov 2009, Nashville, USA (2009)

Yeung, Wai Kit., Chau, Ying., "Protease-sensitive polymeric nanostructure for triggered release", 36th Annual Meeting and Exposition of the Controlled Release Society. July 2009, Copenhagen, Denmark (2009)

Yeung, Wai Kit., Chau, Ying., "Protease-sensitive polymeric vesicles as drug delivery vehicles", 1st Nano Today Conference. August 2009, Singapore (2009)

Li, Qianqian., Chow, King Lau., Chau, Ying., "Self-assembling peptide matrix for probing effects of embedded extracellular matrix mimicking signals on stem cell behavior", WACBE World Congress on Bioengineering 2009. July 2009, Hong Kong (2009)

Chau, Ying., "Strategies for delivering therapeutics to the posterior segment of the eye", Hong Kong Nanotechnology Symposium 2009. Hong Kong, 21 May 2009 (2009)

Zhong, Jieying., Chau, Ying., "Tumor-targeted membrane lysing mediated by tumor-associated protease", AIChE Annual Meeting, Nov 2009, Nashville, USA. AIChE Annual Meeting, Nov 2009, Nashville, USA (2009)

Chau, Ying; Cheung, Alex Chi Yeung , "Ultrasound-enhanced intrascleral delivery of protein”", AIChE Annual Meeting Nov 2009, Nashville, USA (2009)

Chau, Ying., Chau Y., "Control of anti-tumor activity of membrane lytic peptides via MT1-MMP mediation", Center for Cancer Research Retreat, HKU and HKUST. March 2008 (2008)

Li, Qianqian., Chau, Ying., "Directing behavior of neural progenitor cells by altering spatial display of peptide signals in self-assembling matrix", AIChE Annual Meeting. Philadelphia, USA, Nov 2008 (2008)

Wang, Weiping., Yang, Zhimou., Patanavanich, Siamrut., Xu, Bing., Chau, Ying., "Fabrication of peptide nanoparticles via temporal and spatial control of self-assembling", 5th Marie Curie Cutting Edge Conference, Portugal. April 2008 (2008)

Wang, Weiping., Patanavanich, Siamrut., Chau, Ying., "Formation of fractal structures from self-assembling dipeptide derivatives", AIChE Annual Meeting. Philadelphia, USA, Nov 2008 (2008)

Li, Qianqian., Cheung, Alex C Y., Chau, Ying., "Modular approach for designing biomimetic matrix to direct cell behavior", Synthetic Biology 4.0. Hong Kong, October 2008 (2008)

Wang, Weiping., Chau, Ying., "Morphology and size-controlled self-assembling of enzyme-responsive peptides", AIChE Annual Meeting. Philadelphia, USA, Nov 2008 (2008)

Chau, Ying., Wang, Weiping., "Self-assembly of biomimetic peptide nanocages with enzymatic control", AIChE Annual Meeting. Philadelphia, USA, Nov 2008 (2008)

Chau, Ying., Luo, Ying., Li, Qianqian., Cheung, Alex C Y., "Tailoring of self-assembling peptide scaffolds with biofunctional epitopes", AIChE Annual Meeting. Philadelphia, USA, Nov 2008 (2008)

Chau, Ying., Luo, Ying., Li, Qianqian., Cheung, Alex., Langer, Robert., "A designer peptide template for self-assembling biomimetic nanofibrous hydrogel", 1st IEEE-Nanomed Conference, Macau, China. August, 2007 (2007)

Chau, Ying., "Matrix metalloproteinase-activated anticancer nanomedicines", Seminar for Center for Cancer Research, HKUST. 2007 (2007)

Zhong, J.Y., Chau, Ying., "Novel matrix-metalloproteinase-activated polymer-peptide conjugates for targeted anticancer treatment", Center for Cancer Research Retreat, HKUST. May 2007 (2007)

Wang W., Chau, Ying., "Peptide Nanogels for Ocular Drug Delivery", Eye Research Day, Hong Kong. Jan 2007 (2007)

Wang, Weiping., Yang, Zhimou., Xu, Bing., Chau, Ying., "Self-assembling peptide nanoparticles for drug delivery", 3rd International Conference on Bioengineering and Nanotechnology, Singapore. August, 2007 (2007)

Chau, Ying., "A new paradigm in biomedical applications based on protease activation", Medical Engineering Seminar, Hong Kong University. 2006 (2006)

Chau, Ying., "A new paradigm in biomedical applications based on protease activation", School of Chemistry and Chemical Technology, Shanghai Jiao Tong University. 2006 (2006)

Chau, Ying., Panigrahy D., Dang, N., Tan, F., Langer, R., "In vitro and in vivo investigation of new tumortargeting conjugates with MMP sensitive linkers", Controlled Release Society Annual Meeting, Honolulu, Hawaii. 2004 (2004)

Chau, Ying., Langer, R.S., "A novel polymer-peptide-drug conjugate for tumor targeting via MMP mediation", The 7th US-Japan Symposium on Drug Delivery Systems, Maui, Hawaii. 2003 (2003)

Chau, Ying., Langer, R.S., "Important factors in designing targeted delivery of cancer therapeutics via MMP-2 mediation", Second International Symposium on Tumor Targeted Delivery Systems, Rockville, MD. 2002 (2002)

Chau, Ying., Balasubramanian, U., Chu, L., Wang, W.W., Zhou, W.C., "Characterization of trypsin solutions for use in cell culture process development", American Chemical Society National Meeting, San Francisco, CA.. 2000 (2000)

Chau, Ying., Sagar, S., Watson, M., Lee, A., "Adsorption Behavior of Plasmid DNA on Chromatographic Resins", Prep 98" Conference, Washington D.C.. 1998 (1998)