Prof. Richard LAKERVELD's Publications

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Article

Nyande, Baggie Waponde; Nagy, Zoltan K.; Lakerveld, Richard, "Data-driven identification of crystallization kinetics", Aiche Journal, v. 70, (5), May 2024, article number e18333 (2024)

Mendis, Nethrue Pramuditha; Wang, Jiayuan; Lakerveld, Richard, "A Workflow for Crystallization Process Design with Simultaneous Process Optimization and Solvent Selection based on the Perturbed-Chain Statistical Associating Fluid Theory", Chemie Ingenieur Technik, January 2023 (2023)

Mendis, Nethrue Pramuditha; Lakerveld, Richard, "An In Vitro Model for Cocrystal Dissolution with Simultaneous Surface and Bulk Precipitation", Molecular Pharmaceutics, v. 20, (11), November 2023, p. 5486-5499 (2023)

Gupta, Dishika; Nyande, Baggie Waponde; Mathew Thomas, Kiran; Li, Fei; Mak, Andrew T.C.; Lakerveld, Richard, "Induced-charge electroosmosis for rapid mixing of reactive precipitation systems to obtain small and uniform particles", Chemical Engineering Research and Design, v. 190, February 2023, p. 715-729 (2023)

Mendis, Nethrue Pramuditha; Li, Jiatao; Lakerveld, Richard, "Integrated Selection of Coformers, Solvents, and Operating Conditions for Optimal Process and Product Performance of Pharmaceutical Cocrystals", Industrial & Engineering Chemistry Research, v. 62, (33), 14 August 2023, p. 13081-13095 (2023)

Mathew Thomas, Kiran; Nyande, Baggie Waponde; Lakerveld, Richard, "Design and characterization of Kenics static mixer crystallizers", Chemical Engineering Research and Design, v. 179, March 2022, p. 549-563 (2022)

Kwon, Soo Jin; Lakerveld, Richard, "Impact of Cooling Profile on Batch Emulsion Solution Crystallization", Industrial and Engineering Chemistry Research, v. 61, (30), August 2022, p. 11108-11115 (2022)

Kwon, Soo Jin; Mathew Thomas, Kiran; Lakerveld, Richard, "Integrated membrane emulsification and solution cooling crystallization to obtain a narrow and predictable crystal size distribution", Chemical Engineering and Processing - Process Intensification, v. 171, January 2022, article number 108751 (2022)

Wong, Si Nga; Weng, Jingwen; Ip, Ignatius; Chen, Ruipeng; Lakerveld, Richard; Telford, Richard; Blagden, Nicholas; Scowen, I.J.; Chow, Shing Fung, "Rational Development of a Carrier-Free Dry Powder Inhalation Formulation for Respiratory Viral Infections via Quality by Design: A Drug-Drug Cocrystal of Favipiravir and Theophylline", Pharmaceutics, v. 14, (2), 2022 (2022)

Mendis, Nethrue Pramuditha; Wang, Jiayuan; Lakerveld, Richard, "Simultaneous Solvent Selection and Process Design for Continuous Reaction–Extraction–Crystallization Systems", Industrial & Engineering Chemistry Research, v.61, (31), August 2022, p. 11504-11517 (2022)

Gao, Yu; Liu, Kun; Lakerveld, Richard; Ding, Xiaoyun, "Staged Assembly of Colloids Using DNA and Acoustofluidics", Nano Letters, v. 22, (17), 2022, p. 6907-6915 (2022)

Nyande, Baggie Waponde; Mathew Thomas, Kiran; Lakerveld, Richard, "CFD Analysis of a Kenics Static Mixer with a Low Pressure Drop under Laminar Flow Conditions", Industrial & Engineering Chemistry Research, v. 60, (14), March 2021, p. 5264-5277 (2021)

Mathew Thomas, Kiran; Kwon, Soo Jin; Lakerveld, Richard, "Continuous Protein Crystallization in Mixed-Suspension Mixed-Product-Removal Crystallizers", Crystal Growth and Design, v. 21, (2), 3 February 2021, p. 757-769 (2021)

Kang, Hong; Lin, Tong; Xu, Xiaojin; Jia, Qing-Shan; Lakerveld, Richard; Wei, Bryan, "DNA dynamics and computation based on toehold-free strand displacement", Nature Communications, v. 12, (1), August 2021, article number 4994 (2021)

Xuan, Bianfei; Chen, Yu Chee Sonia; Wong, Kong Ching; Chen, Ruipeng; Lo, Po Sang; Lakerveld, Richard; Tong, Henry Hoi Yee; Chow, Shing Fung, "Impact of cocrystal solution-state stability on cocrystal dissociation and polymorphic drug recrystallization during dissolution", International Journal of Pharmaceutics, v. 610, December 2021, article number 121239 (2021)

Capdevila-Echeverria, Jose; Wang, Jiayuan; Lakerveld, Richard; ter Horst, Joop H., "Process modeling and optimization of continuous chiral resolution by integration of membrane and crystallization technologies", Journal of Membrane Science, v. 632, August 2021, article number 119359 (2021)

Mendis, Nethrue Pramuditha; Wang, Jiayuan; Lakerveld, Richard, "A Thermodynamic Approach for Simultaneous Solvent and Process Design of Continuous Reactive Crystallization with Recycling", Computer Aided Chemical Engineering, v. 48, January 2020, p. 805-810 (2020)

Fajrial, Apresio K.; Liu, Kun; Gao, Yu; Gu, Junhao; Lakerveld, Richard; Ding, Xiaoyun, "Characterization of Single-Cell Osmotic Swelling Dynamics for New Physical Biomarkers", Analytical Chemistry, v. 93, (3), 26 January 2021, p. 1317-1325 (2020)

Chen, Ruipeng; Weng, Jingwen; Chow, Shing Fung; Lakerveld, Richard, "Integrated Continuous Crystallization and Spray Drying of Insulin for Pulmonary Drug Delivery", Crystal Growth & Design, v. 21, (1), December 2021, p. 501-511 (2020)

Mathew Thomas, Kiran; Lakerveld, Richard, "An Airlift Crystallizer for Protein Crystallization", Industrial & Engineering Chemistry Research, v. 58, (44), November 2019, p. 20381-20391 (2019)

Weng, Jingwen; Wong, Singa; Xu, Xiaoyan; Xuan, Bianfei; Wang, Chenguang; Chen, Ruipeng; Sun, Changquan Calvin; Lakerveld, Richard; Kwok, Philip Chi Lip; Chow, Shing Fung, "Cocrystal Engineering of Itraconazole with Suberic Acid via Rotary Evaporation and Spray Drying", Crystal Growth and Design, 2019 (2019)

Gao, Yu; Lakerveld, Richard, "Feedback Control for Shaping Density Distributions of Colloidal Particles in Microfluidic Devices", Lab on a Chip, v. 19, (13), July 2019, p. 2168-2177 (2019)

Gao, Yu; Lakerveld, Richard, "Gain scheduling PID control for directed self-assembly of colloidal particles in microfluidic devices", AIChE Journal, February 2019, article number e16582 (2019)

Hadiwinoto, Gabriela Daisy; Kwok, Philip Chi Lip; Tong, Henry H.Y.; Wong, Singa; Chow, Shingfung; Lakerveld, Richard, "Integrated Continuous Plug-Flow Crystallization and Spray Drying of Pharmaceuticals for Dry Powder Inhalation", Industrial and Engineering Chemistry Research, v. 58, (36), September 2019, p. 16843-16857 (2019)

Khodadadian, Fatemeh; De La Garza, Francisco Galnares; Van Ommen, J. Ruud; Stankiewicz, Andrzej I.; Lakerveld, Richard, "The application of automated feedback and feedforward control to a LED-based photocatalytic reactor", Chemical Engineering Journal, v.362, April 2019, p. 375-382 (2019)

Lakerveld, Richard, "Control system implementation and plant-wide control of continuous pharmaceutical manufacturing pilot plant (end-to-end manufacturing process)", Computer Aided Chemical Engineering: Process Systems Engineering for Pharmaceutical Manufacturing, v. 41, 2018, p. 403-430 (2018)

Li, Fei; Lakerveld, Richard, "Electric-Field-Assisted Protein Crystallization in Continuous Flow", Crystal Growth & Design, v. 18, (5), May 2018, p. 2964-2971 (2018)

Gao, Yu; Lakerveld, Richard, "Feedback control for defect-free alignment of colloidal particles", LAB ON A CHIP, v. 18, (14), July 2018, p. 2099-2110 (2018)

Wang, Jiayuan; Lakerveld, Richard, "Integrated Solvent and Process Optimization Using PC-SAFT for Continuous Crystallization with Energy-intensive Solvent Separation for Recycling", Computer Aided Chemical Engineering, v. 44, July 2018, p. 1051-1056 (2018)

Wang, Jiayuan; Lakerveld, Richard, "Continuous Membrane-Assisted Crystallization To Increase the Attainable Product Quality of Pharmaceuticals and Design Space for Operation", Industrial & Engineering Chemistry Research, v. 56, (19), 26 April 2017, p. 5705-5714 (2017)

Li, Fei; Lakerveld, Richard, "Influence of Alternating Electric Fields on Protein Crystallization in Microfluidic Devices with Patterned Electrodes in a Parallel-Plate Configuration", Crystal Growth & Design, v. 17, (6), June 2017, p. 3062-3070 (2017)

Wang, Jiayuan; Lakerveld, Richard, "Integrated solvent and process design for continuous crystallization and solvent recycling using PC-SAFT", AIChE Journal, 27 October 2017 (2017)

Mesbah, Ali; Paulson, Joel.A.; Lakerveld, Richard; Braatz, Richard D., "Model Predictive Control of an Integrated Continuous Pharmaceutical Manufacturing Pilot Plant", Organic Process Research & Development, v. 21, (6), June 2017, p. 844-854 (2017)

Gao, Yu; Mi, Yongli; Lakerveld, Richard, "An Optimization-based Approach for Structural Design of Self-assembled DNA Tiles", AIChE Journal, 3 November 2016 (2016)

Kacker, Rohit ; Salvador, Pedro M. ; Sturm, Guidso S.J. ; Stefanidis, Georgios D. ; Lakerveld, Richard; Nagy, Zoltan K. ; Kramer, Herman J.M. , "Microwave Assisted Direct Nucleation Control for Batch Crystallization: Crystal Size Control with Reduced Batch Time", Crystal growth & design, v. 16, (1), 2016, p. 440-446 (2016)

Khodadadian, Fatemeh; Poursaeidesfahani, Ali; Li, Zonghan; Van Ommen, J. Ruud; Andrzej I. Stankiewicz, Andrzej; Lakerveld, Richard, "Model-Based Optimization of a Photocatalytic Reactor with Light-Emitting Diodes", Chemical engineering & technology, v. 39, (10), 2016, p. 1946-1954 (2016)

Ramaswamy, Sivaraman ; Lakerveld, Richard; Barton, Paul I. ; Stephanopoulos, George , "Controlled formation of nanostructures with desired geometries: Part 3. Dynamic modeling and simulation of directed self-assembly of nanoparticles through adaptive finite state projection", Industrial and Engineering Chemistry Research, v. 54, (16), 2015, April, p. 4371-4384 (2015)

Lakerveld, Richard; Van Krochten, Jeroen J. H. ; Kramer, Herman J. M. , "An Air-Lift Crystallizer Can Suppress Secondary Nucleation at a Higher Supersaturation Compared to a Stirred Crystallizer", Crystal growth & design v. 14, (7), July 2014, p. 3264-3275 (2014)

Zhang, Haitao ; Lakerveld, Richard; Heider, Patrick L. ; Tao, Mengying ; Su, Min ; Testa, Christopher J. ; D'Antonio, Alyssa N. ; Barton, Paul I. ; Braatz, Richard D. ; Trout, Bernhardt L. ; Myerson, Allan S. ; Jensen, Klavs F. ; Evans, James M. B. , "Application of Continuous Crystallization in an Integrated Continuous Pharmaceutical Pilot Plant", Crystal growth & design v. 14, (5), May 2014, p. 2148-2157 (2014)

Heider, Patrick L. ; Born, Stephen C. ; Basak, Soubir ; Benyahia, Brahim ; Lakerveld, Richard; Zhang, Haitao ; Hogan, Rachael ; Buchbinder, Louis ; Wolfe, Aaron ; Mascia, Salvatore ; Evans, James M. B. ; Jamison, Timothy F. ; Jensen, Klavs F. , "Development of a Multi-Step Synthesis and Workup Sequence for an Integrated, Continuous Manufacturing Process of a Pharmaceutical", Organic process research & development v. 18, (3), March 2014, p. 402-409 (2014)

Lakerveld, R.; Sturm, G.S.J. ; Stankiewicz, A.I. ; Stefanidis, G.D. , "Integrated design of microwave and photocatalytic reactors. Where are we now?", Current Opinion in Chemical Engineering v. 5, 2014, p. 37-41 (2014)

Richard Lakerveld; Brahim Benyahia ; Patrick L. Heider ; Haitao Zhang ; Richard D. Braatz ; Paul I. Barton , "Averaging Level Control to Reduce Off-Spec Material in a Continuous Pharmaceutical Pilot Plant", Processes v. 1, no. 3, p. 330-348 (2013)

Mascia, Salvatore ; Heider, Patrick L. ; Zhang, Haitao ; Lakerveld, Richard; Benyahia, Brahim ; Barton, Paul I. ; Braatz, Richard D. ; Cooney, Charles L. ; Evans, James M. B. ; Jamison, Timothy F. ; Jensen, Klavs F. ; Myerson, Allan S. ; Trout, Bernhardt , "End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation", Angewandte Chemie (International ed.) v. 52, (47), November 2013, p. 12359-12363 (2013)

Lakerveld, Richard; Benyahia, Brahim ; Braatz, Richard D. ; Barton, Paul I. , "Model-Based Design of a Plant-Wide Control Strategy for a Continuous Pharmaceutical Plant", AIChE journal v. 59, (10), October 2013, p. 3671-3685 (2013)

Benyahia, Brahim ; Lakerveld, Richard; Barton, Paul I. , "A Plant-Wide Dynamic Model of a Continuous Pharmaceutical Process", Industrial & engineering chemistry research v. 51, (47), November 2012, p. 15393-15412 (2012)

Lakerveld, Richard; Stephanopoulos, George ; Barton, Paul I. , "A master-equation approach to simulate kinetic traps during directed self-assembly", The Journal of chemical physics v. 136, (18), May 2012, Article number 184109 (2012)

Soare, Anamaria ; Lakerveld, Richard; Van Royen, Jurjen ; Zocchi, Giorgia ; Stankiewicz, Andrzej I. ; Kramer, Herman J. M. , "Minimization of Attrition and Breakage in an Airlift Crystallizer", Industrial & engineering chemistry research v. 51, (33), August 2012, p. 10895-10909 (2012)

Lakerveld, Richard; Verzijden, Nelleke G. ; Kramer, Herman ; Jansens, Peter ; Grievink, Johan , "Application of Ultrasound for Start-Up of Evaporative Batch Crystallization of Ammonium Sulfate in a 75-L Crystallizer", AIChE journal v. 57, (12), December 2011, p. 3367-3377 (2011)

Lakerveld, Richard; Stephanopoulos, George ; Barton, Paul I. , "Towards robust fabrication of non-periodic nanoscale systems via directed self assembly", Computer-aided chemical engineering v. 29, 2011, p. 1603-1607 (2011)

Lakerveld, Richard; Kramer, Herman J. M. ; Stankiewicz, Andrzej I. ; Grievink, Johan , "Application of generic principles of process intensification to solution crystallization enabled by a task-based design approach", Chemical engineering and processing v. 49, September 2010, p. 979-991 (2010)

Lakerveld, Richard; Kuhn, Jelan ; Kramer, Herman J. M. ; Jansens, Peter J. ; Grievink, Johan , "Membrane assisted crystallization using reverse osmosis: Influence of solubility characteristics on experimental application and energy saving potential", Chemical engineering science v. 65, (9), May 2010, p. 2689-2699 (2010)

Kuhn, Jelan ; Lakerveld, Richard; Kramer, Herman J. M. ; Grievink, Johan ; Jansens, Peter J. , "Characterization and Dynamic Optimization of Membrane-Assisted Crystallization of Adipic Acid", Industrial & engineering chemistry research v. 48, (11), June 2009, p. 5360-5369 (2009)

Lakerveld, Richard; Kramer, Herman J. M. ; Jansens, Peter J. ; Grievink, Johan , "The application of a task-based concept for the design of innovative industrial crystallizers", Computers & chemical engineering v. 33, (10), October 2009, p. 1692-1700 (2009)

Lakerveld, R; Bildea, CS ; Almeida-Rivera, CP , "Exothermic isomerization reaction in a reactive flash: Steady-state behavior", Industrial & engineering chemistry research v. 44, (10), May 2005, p. 3815-3822 (2005)

Book chapter

Khodadadian, Fatemey; Nasalevich, Maxim; Kapteijn, Freek; Stankiewicz, Andrzej; Lakerveld, Richard; Gascon, Jorge, "Photocatalysis: Past Achievements and Future Trends", Alternative Energy Sources for Green Chemistry, Editors: Georgios Stefanidis, Andrzej Stankiewicz. Cambridge, UK : The Royal Society of Chemistry, 2016, p. 227-269, From Book Series: Green Chemistry Series. (2016)

Conference paper

Mendis, Nethrue Pramuditha; Lakerveld, Richard, "A Thermodynamic Approach for Simultaneous Solvent, Coformer, and Process Optimization of Continuous Cocrystallization Processes", Proceedings of the 14th International Symposium on Process Systems Engineering – PSE 2021+, v. 49, June 2022, p. 2179-2184 (2022)

Nyande, Baggie Waponde; Mathew Thomas, Kiran; Lakerveld, Richard, "A 3D-Printed Low Pressure-Drop Plug-Flow Crystallizer for Protein Crystallization", 21st International Symposium on Industrial Crystallization, Online, 30 August 2021 - 2 September 2021 (2021)

Lo, Po Sang; Lakerveld, Richard, "The Development of a Crystallization-Based Process for the Enantiomeric Enrichment of an Active Ingredient Derived from Traditional Chinese Medicine", 2021 AIChE Annual Meeting, Virtual, Separations Division (02), 15 November 2021 (2021)

Nyande, Baggie Waponde; Gao, Yu; Lakerveld, Richard, "A Dynamic Model for Automated Control of Directed Self-assembly of Colloidal Particles at Low Densities", Computer Aided Chemical Engineering, v. 46, 2019, p. 1783-1788 (2019)

Gao, Yu; Lakerveld, Richard, "Automated Open-loop Control of Directed Self-assembly With Multiple Electrokinetic Actuators in Microfluidic Devices", Computer Aided Chemical Engineering, v. 46, 2019, p. 43-48 (2019)

Kacker, R.; Lakerveld, Richard; Kramer, Herman J.M., "Microwave Assisted Fines Control during Crystallization", BIWIC 2014: 21st International Workshop on Industrial Crystallization, University of Rouen, France, 10-12 September 2014, p. 97 (2014)

Lakerveld, R.; Benyahia, B. ; Heider, P.L. ; Zhang, H. ; Wolfe, A. ; Testa, C. ; Ogden, S. ; Hersey, D.R. ; Mascia, S. ; Evans, J.M.B. ; Braatz, R.D. ; Barton, P.I. , "The application of an automated plant-wide control strategy for a continuous pharmaceutical pilot plant", Proceedings of the American Control Conference 2014, p. 3512-3517 (2014)

Lakerveld, R.; Kramer, H.J.M. ; Stankiewicz, A.I. ; Jansens, P.J. ; Grievink, J. , "Opportunities for process intensification in crystallization: application of air-mixed devices", EPIC 2009 Conference Proceedings Venice, Italy, 2009 (2009)

Lakerveld, R.; Kramer, H.J.M. ; Jansens, P.J. ; Grievink, J. , "The Application of a Task Based Design Approach to Solution Crystallization", FOCAPD Conference Proceedings Breckenridge, Colorado, United States, 2009 (2009)

Lakerveld, Richard; Kramer, Herman J. M. ; Jansens, Peter J. ; Grievink, Johan , "The Application of a Task-Based Concept for Design of Innovative Industrial Crystallizers", Computer-aided chemical engineering v. 27, 2009, p. 909-914 (2009)

Lakerveld, R.; Kramer, H.J.M. ; Jansens, P.J. ; Grievink, J. , "A task based design approach for solution crystallization", BIWIC 2008 - 15th International Workshop on Industrial Crystallization Aachen, Germany, 10-12 September 2008 p. 95-102 (2008)

Lakerveld, R.; Kuhn, J. ; Bosch, M.A. ; Kramer, H.J.M. ; Jansens, P.J. ; Grievink, J. , "Membrane Assisted Evaporative Crystallization: Optimization of Task Supersaturation Generation", 17th International Symposium on Industrial Crystallization Conference Proceedings Maastricht, the Netherlands, 2008, p. 827-834 (2008)

Lakerveld, R.; Kramer, H.J.M. ; Jansens, P.J. ; Grievink, J. , "Solution Crystallization in a Bubble Column Optimization of the task: Crystal Growth", 17th International Symposium on Industrial Crystallization Conference Proceedings Maastricht, the Netherlands, 2008, p. 819-826 (2008)

Lakerveld, R.; Verzijden, P.G. ; Kramer, H.J.M. ; Jansens, P.J. ; Grievink, J. , "The Application of Ultrasound for Seeding Purposes Optimization of the task: Nucleation", 17th International Symposium on Industrial Crystallization Conference Proceedings Maastricht, the Netherlands, 2008, p. 835-842 (2008)

Kramer, H.J.M. ; Lakerveld, R.; Jansens, P.J. ; Grievink, J. , "Novel design strategies for solution crystallization processes", AIChE Annual Meeting, Conference Proceedings 2007 (2007)

Lakerveld, R.; Kalbasenka, A. N. ; Kramer, H. J. M. ; Grievink, J. ; Jansens, P. J. , "The application of different seeding techniques for solution crystallization of ammonium sulphate", BIWIC 2007 2007, p. 221-228 (2007)

Lakerveld, R.; Djatmiko, M. E. ; Kramer, H. J. M. ; Jansens, P. J. ; Grievink, J. , "Task based design techniques for solution crystallisation processes: Application to a bubble column setup", BIWIC 2006 2006, p. 114-121 (2006)